Anastrozole, sold under the brand name Arimidex among others, is an antiestrogenic medication used in addition to other treatments for breast cancer.[7][8] Specifically it is used for hormone receptor-positive breast cancer.[8] It has also been used to prevent breast cancer in those at high risk.[8] It is taken orally
Common side effects of anastrozole include hot flashes, altered mood, joint pain, and nausea.[8][7] Severe side effects include an increased risk of heart disease and osteoporosis.[8] Use during pregnancy may harm the baby.[8] Anastrozole is in the aromatase-inhibiting family of medications.[8] It works by blocking the production of estrogens in the body, and hence has antiestrogenic effects.[8]
Anastrozole was patented in 1987 and was approved for medical use in 1995.[9][10] It is on the World Health Organization’s List of Essential Medicines.[11] Anastrozole is available as a generic medication.[8] In 2022, it was the 179th most commonly prescribed medication in the United States, with more than 2 million prescriptions
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